Therefore, for fixing this Windows problem you will have to access Registry and modify the values by yourselves. These third-party apps are making changes on the Registry and by modifying the default values the ctrl+alt+del feature will stop working. Well, ctrl+alt+del might not work after installing third-party apps, or after updating the system with an unofficial firmware. Unfortunately, there are situations in which the ctrl alt del sequence is not working on our Windows 10 device.
If you want to open Task Manager on your Windows, or Windows device then you will have to use a combination of three keyboard buttons: ctrl+alt+del.